Born in Berlin in 1962, he began his training and professional work as a sound technician at the broadcast stations and recording studios of the former German Democratic Republic. From 1987 until 1993 he studied sound engineering at the Musikhochschule Hanns Eisler in Berlin, where he founded and headed the studio for electroacoustic music until 2002. From 1999 to 2004 he also taught at the Musikhochschule and at the media faculty of the Bauhaus University in Weimar. Together with Volker Straebel he co-directed the Electronic Studio at the Technische Universität Berlin in 2009–12.
He has given workshops, lectures and talks on electroacoustic composition and programming around the world. He works as a programmer and sound engineer for contemporary music, sound and media art. For more than 15 years he has been developing and performing his own musical projects, compositions, sound installations and video art, with performances at numerous festivals worldwide. He has ongoing collaborations with musicians, dancers and visual artists. Andre Bartetzki has received grants and fellowships at the ZKM Karlsruhe and other places.